ZAK Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2726111

Détail du produit

Antigène: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ZAK protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MLTK (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Autre désignation: Mltk (ZAK Produits)

Synonymes: MLTK Protein, RGD1561394 Protein, AZK Protein, MLK7 Protein, MLT Protein, MRK Protein, mlklak Protein, pk Protein, AV006891 Protein, B230120H23Rik Protein, MLTKalpha Protein, MLTKbeta Protein, mitogen-activated protein kinase kinase kinase 20 Protein, Map3k20 Protein, MAP3K20 Protein

Sujet: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire: 91 kDa

NCBI Accession: NP_057737