MMP14 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2726152

Détail du produit

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MMP14 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MMP-14 / MT1-MMP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: Mmp-14,mt1-Mmp (MMP14 Produits)

Synonymes: MMP1 Protein, MMP-14 Protein, MMP-X1 Protein, MT-MMP Protein, MT-MMP 1 Protein, MT1-MMP Protein, MT1MMP Protein, MTMMP1 Protein, mmp-x1 Protein, mt1-mmp Protein, mtmmp1 Protein, AI325305 Protein, MT-MMP-1 Protein, sabe Protein, Mt1-mmp Protein, MT-MMPbeta Protein, cb386 Protein, sb:cb386 Protein, wu:fb72b09 Protein, mmp14 Protein, matrix metallopeptidase 14 Protein, matrix metallopeptidase 14 (membrane-inserted) Protein, matrix metallopeptidase 14b (membrane-inserted) Protein, matrix metallopeptidase 14a (membrane-inserted) Protein, matrix metallopeptidase 14 L homeolog Protein, MMP14 Protein, mmp14 Protein, Mmp14 Protein, mmp14b Protein, mmp14a Protein, mmp14.L Protein

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Poids moléculaire: 53.8 kDa

NCBI Accession: NP_004986

Pathways: Autophagy