MR1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2726311

Détail du produit

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MR1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MR1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Autre désignation: Mr1 (MR1 Produits)

Synonymes: YFV Protein, hlals Protein, MGC154362 Protein, MR1 Protein, DKFZp468C1823 Protein, HLALS Protein, H2ls Protein, Hlals Protein, MHC class I antigen YF5 Protein, major histocompatibility complex, class I-related Protein, major histocompatibility complex, class I-related L homeolog Protein, YF5 Protein, MR1 Protein, mr1.L Protein, mr1 Protein, Mr1 Protein

Sujet: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

Poids moléculaire: 39.2 kDa

NCBI Accession: NP_001522

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints