MR1 Protein (Fc Tag)
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- Antigène Voir toutes MR1 Protéines
- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MR1 protéine est marqué à la Fc Tag.
- Séquence
- MR1 (R23-Met302)+hFc(GLU99-ALA330)
- Attributs du produit
- Tagged Protein: C-Human Fc tag
- Purification
- affinity purification
- Top Product
- Discover our top product MR1 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Agent conservateur
- Without preservative
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Date de péremption
- 12 months
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- Antigène
- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
- Autre désignation
- MR1 (MR1 Produits)
- Synonymes
- YFV Protein, hlals Protein, MGC154362 Protein, MR1 Protein, DKFZp468C1823 Protein, HLALS Protein, H2ls Protein, Hlals Protein, MHC class I antigen YF5 Protein, major histocompatibility complex, class I-related Protein, major histocompatibility complex, class I-related L homeolog Protein, YF5 Protein, MR1 Protein, mr1.L Protein, mr1 Protein, Mr1 Protein
- Sujet
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Synonymes: HLALS
Description: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. [provided by RefSeq, Jul 2015] - Poids moléculaire
- 56.32 kDa
- UniProt
- Q95460
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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