MSH2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2726435

Détail du produit

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MSH2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MSH2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Autre désignation: Msh2 (MSH2 Produits)

Synonymes: COCA1 Protein, FCC1 Protein, HNPCC Protein, HNPCC1 Protein, LCFS2 Protein, AI788990 Protein, wu:fc06b02 Protein, wu:fc13e09 Protein, zgc:55333 Protein, ATMSH2 Protein, MUTS homolog 2 Protein, msh2 Protein, mutS homolog 2 Protein, mutS homolog 2 (E. coli) Protein, MUTS homolog 2 Protein, mutS homolog 2 L homeolog Protein, MutS protein homolog 2 Protein, MSH2 Protein, Msh2 Protein, msh2 Protein, msh2.L Protein

Sujet: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 104.6 kDa

NCBI Accession: NP_000242

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response