NEIL2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2727072

Détail du produit

Antigène: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NEIL2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human NEIL2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Autre désignation: Neil2 (NEIL2 Produits)

Synonymes: NEH2 Protein, NEI2 Protein, Gm1212 Protein, nei like DNA glycosylase 2 Protein, nei like 2 (E. coli) Protein, NEIL2 Protein, Neil2 Protein

Sujet: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM, Mar 2008].

Poids moléculaire: 36.6 kDa

NCBI Accession: NP_001129218

Pathways: Réparation de l'ADN