OTX2 Protein (His tag)

N° du produit ABIN2728063

Détail du produit

Antigène: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette OTX2 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human OTX2 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Autre désignation: Otx2 (OTX2 Produits)

Synonymes: CPHD6 Protein, MCOPS5 Protein, E130306E05Rik Protein, id:ibd2915 Protein, zOtx2 Protein, zgc:136535 Protein, zotx-2 Protein, Xotx-2 Protein, Xotx2 Protein, otx-2 Protein, otx2 Protein, orthodenticle homeobox 2 Protein, orthodenticle homeobox 2 S homeolog Protein, orthodenticle homeobox 2 L homeolog Protein, OTX2 Protein, Otx2 Protein, otx2 Protein, otx2.S Protein, otx2.L Protein

Sujet: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

Poids moléculaire: 31.6 kDa

NCBI Accession: NP_068374

Pathways: Dopaminergic Neurogenesis