PADI1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2728122

Détail du produit

Antigène: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PADI1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PADI1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Autre désignation: Padi1 (PADI1 Produits)

Synonymes: HPAD10 Protein, PAD1 Protein, PDI Protein, PDI1 Protein, AV236283 Protein, Pdi1 Protein, peptidyl arginine deiminase 1 Protein, peptidyl arginine deiminase, type I Protein, PADI1 Protein, Padi1 Protein

Sujet: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.

Poids moléculaire: 74.5 kDa

NCBI Accession: NP_037490