PCDHA4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2728388

Détail du produit

Antigène: PCDHA4 (Protocadherin alpha 4 (PCDHA4))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PCDHA4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PCDHA4 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PCDHA4 (Protocadherin alpha 4 (PCDHA4))

Autre désignation: Pcdha4 (PCDHA4 Produits)

Synonymes: CNR1 Protein, CNRN1 Protein, CRNR1 Protein, PCDH-ALPHA4 Protein, Cnr1 Protein, Crnr1 Protein, R75250 Protein, PCDHA4 Protein, CNRv4 Protein, Pcdha4 Protein, protocadherin alpha 4 Protein, protocadherin alpha-4 Protein, PCDHA4 Protein, Pcdha4 Protein, LOC100713594 Protein, LOC100629843 Protein

Sujet: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Poids moléculaire: 82.9 kDa

NCBI Accession: NP_113688