POGLUT1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes POGLUT1 Protéines
- POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette POGLUT1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human POGLUT1 / KTELC1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product POGLUT1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
- Autre désignation
- Poglut1,ktelc1 (POGLUT1 Produits)
- Synonymes
- C3orf9 Protein, CLP46 Protein, KDELCL1 Protein, KTELC1 Protein, MDSRP Protein, Rumi Protein, hCLP46 Protein, MDS010 Protein, 9630046K23Rik Protein, Ktelc1 Protein, protein O-glucosyltransferase 1 Protein, POGLUT1 Protein, Poglut1 Protein
- Sujet
- This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 46 kDa
- NCBI Accession
- NP_689518
- Pathways
- Signalisation Notch
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