PRR5 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2729850

Détail du produit

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PRR5 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PRR5 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Autre désignation: Prr5 (PRR5 Produits)

Synonymes: AU043908 Protein, Arhgap8 Protein, C030017C09Rik Protein, C78947 Protein, Protor-1 Protein, Protor1 Protein, FLJ20185k Protein, PP610 Protein, PROTOR-1 Protein, PROTOR1 Protein, pp610 Protein, protor1 Protein, protor2 Protein, proline rich 5 (renal) Protein, proline rich 5 Protein, proline rich 5 L homeolog Protein, Prr5 Protein, PRR5 Protein, prr5.L Protein

Sujet: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

Poids moléculaire: 41.4 kDa

NCBI Accession: NP_056181

Pathways: Signalisation PI3K-Akt