PTBP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730034

Détail du produit

Antigène: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PTBP1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PTBP1 (PTB) (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Autre désignation: Ptbp1 (Ptb) (PTBP1 Produits)

Synonymes: HNRNP-I Protein, HNRNPI Protein, HNRPI Protein, PTB Protein, PTB-1 Protein, PTB-T Protein, PTB2 Protein, PTB3 Protein, PTB4 Protein, pPTB Protein, Ptb Protein, hnrpi Protein, hnrnp-I Protein, vgrbp60 Protein, AA407203 Protein, AL033359 Protein, Pybp Protein, Pybp1 Protein, Pybp2 Protein, ptbp1 Protein, wu:fb99f12 Protein, zgc:110689 Protein, ptb Protein, ATPTB1 Protein, POLYPYRIMIDINE TRACT-BINDING Protein, POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 Protein, T4P13.16 Protein, T4P13_16 Protein, polypyrimidine tract-binding protein 1 Protein, PTBP1 Protein, polypyrimidine tract binding protein 1 Protein, polypyrimidine tract binding protein 1 S homeolog Protein, polypyrimidine tract-binding protein Protein, polypyrimidine tract binding protein 1a Protein, polypyrimidine tract binding protein 1 L homeolog Protein, polypyrimidine tract-binding protein 1 Protein, PTBP1 Protein, ptbp1.S Protein, NAEGRDRAFT_80143 Protein, LOC100285404 Protein, Ptbp1 Protein, ptbp1a Protein, ptbp1.L Protein, PTB1 Protein, LOC100061673 Protein

Sujet: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire: 58.9 kDa

NCBI Accession: NP_114367

Pathways: Regulation of Muscle Cell Differentiation