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PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

PC Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2730237
  • Antigène Voir toutes PC Protéines
    PC (Pyruvate Carboxylase (PC))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 3
    Origine
    • 2
    • 2
    Humain
    Source
    • 3
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PC protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Pyruvic carboxylase (PC) (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PC Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PC (Pyruvate Carboxylase (PC))
    Autre désignation
    Pyruvic Carboxylase (Pc) (PC Produits)
    Synonymes
    BcDNA Protein, BcDNA:GH06348 Protein, Dmel\\CG1516 Protein, PC Protein, pyc Protein, wu:fb82g08 Protein, wu:fj85g01 Protein, PCX Protein, BA4157 Protein, Pc Protein, Pcb Protein, PCB Protein, Pcx Protein, Pyruvate carboxylase Protein, pyruvate carboxylase b Protein, PYruvate Carboxylase Protein, pyruvate carboxylase Protein, pyruvate carboxylase Pyr1 Protein, PCB Protein, pcxb Protein, pyc-1 Protein, PC Protein, pyc Protein, pyr1 Protein, CNF00650 Protein, PYC1 Protein, Ndas_1152 Protein, Ilyop_2503 Protein, Calni_0495 Protein, Ftrac_1004 Protein, Plabr_3574 Protein, Sgly_2936 Protein, Celly_0558 Protein, Hipma_0131 Protein, Halhy_1567 Protein, Mesop_1269 Protein, Pcx Protein, Pc Protein
    Sujet
    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
    Poids moléculaire
    127.3 kDa
    NCBI Accession
    NP_001035806
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