RPSA/Laminin Receptor Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730920

Détail du produit

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RPSA/Laminin Receptor protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Ribosomal protein SA (RPSA), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Abstract: RPSA Produits

Synonymes: 37LRP Protein, 67LR Protein, LBP/p40 Protein, LRP/LR Protein, LamR Protein, rpsa Protein, LamR1 Protein, RPSA Protein, LAMBR Protein, LAMR1 Protein, LBP Protein, LRP Protein, NEM/1CHD4 Protein, SA Protein, lamR Protein, p40 Protein, 67kDa Protein, 67lr Protein, AL022858 Protein, Lamr Protein, Lamr1 Protein, Lamrl1 Protein, MLR Protein, P40 Protein, P40-3 Protein, P40-8 Protein, lamr1 Protein, zgc:55831 Protein, zgc:77824 Protein, DMRT1 Protein, 40S ribosomal protein SA Protein, 67kD laminin receptor Protein, ribosomal protein SA Protein, rssa Protein, rpsa Protein, RPSA Protein, Rpsa Protein, LOC100144340 Protein

Sujet: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 32.7 kDa

NCBI Accession: NP_001012321

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly