RSPO2 Protéine

N° du produit ABIN2731227

Détail du produit

Antigène: RSPO2 (R-Spondin 2 (RSPO2))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: CHO Cells

Application: Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human RSPO2 protein expressed in CHO cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: R-Spondin-2 enhances BMP-2 mediated differentiation of MC3T3-E1 cells.

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Conseil sur la manipulation: Resuspend the protein in the desired concentration in proper buffer

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RSPO2 (R-Spondin 2 (RSPO2))

Autre désignation: Rspo2 (RSPO2 Produits)

Synonymes: RGD1562331 Protein, CRISTIN2 Protein, 2610028F08Rik Protein, AA673245 Protein, D430027K22 Protein, ftls Protein, R-spondin 2 Protein, R-spondin 2 L homeolog Protein, Rspo2 Protein, rspo2.L Protein, rspo2 Protein, RSPO2 Protein

Sujet: This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 24.4 kDa

NCBI Accession: NP_848660