SPHK1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes SPHK1 Protéines
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SPHK1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human Sphingosine kinase 1 (SPHK1) (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPHK1 Protéine
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Sphingosine Kinase 1 (SPHK1) (AA 1-384) (Active) protein (GST tag)
SPHK1 Origine: Humain Hôte: Insect cells (Sf21) Recombinant SDS, Func Active
Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (GST tag)SPHK1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Sphingosine Kinase 1 (SPHK1) (AA 261-353) protein (GST tag)SPHK1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Sphingosine Kinase 1 (SPHK1) (Active) proteinSPHK1 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
Sphingosine Kinase 1 (SPHK1) protein (GST tag,His tag)SPHK1 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (Strep Tag)Crystallography grade SPHK1 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Sphingosine Kinase 1 (SPHK1) (AA 1-382) protein (Strep Tag)Crystallography grade SPHK1 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- Abstract
- SPHK1 Produits
- Synonymes
- CG1747 Protein, Dmel\\CG1747 Protein, SK1 Protein, Sphk1 Protein, SPHK1 Protein, F18E5.160 Protein, F18E5_160 Protein, sphingosine kinase 1 Protein, SPHK Protein, 1110006G24Rik Protein, Sk1 Protein, Spk1 Protein, Sphingosine kinase 1 Protein, sphingosine kinase 1 Protein, sphingosine kinase 1 L homeolog Protein, Sk1 Protein, SPHK1 Protein, sphk1.L Protein, Sphk1 Protein
- Sujet
- The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 43.8 kDa
- NCBI Accession
- NP_068807
- Pathways
- VEGF Signaling
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