SPHK2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732579

Détail du produit

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SPHK2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Sphingosine kinase 2 / SPK2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Autre désignation: Sphingosine Kinase 2,spk2 (SPHK2 Produits)

Synonymes: CG2159 Protein, CG32484 Protein, Dmel\\CG32484 Protein, SK2 Protein, Sphk2 Protein, sk2 Protein, DKFZp469F224 Protein, SK 2 Protein, SK-2 Protein, SPK 2 Protein, SPK-2 Protein, C76851 Protein, Sphingosine kinase Protein, sphk2 Protein, Sphingosine kinase 2 Protein, sphingosine kinase 2 Protein, sphK2 Protein, Sk2 Protein, SPHK2 Protein, Sphk2 Protein

Sujet: This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 69 kDa

NCBI Accession: NP_064511

Pathways: VEGF Signaling