TAPBP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2733221

Détail du produit

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TAPBP protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Tapasin (TAPBP) (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: Tapasin (Tapbp) (TAPBP Produits)

Synonymes: SI:dZ179B20.1 Protein, SI:dZ179B20.3 Protein, SI:dZ179B20.7 Protein, mhc1uda Protein, mhc1ufa Protein, tpsn Protein, zgc:109814 Protein, tapbp Protein, TAPBP Protein, D17Wsu91e Protein, TPN Protein, NGS17 Protein, TAPA Protein, TPSN Protein, TAP binding protein (tapasin), tandem duplicate 1 Protein, TAP binding protein Protein, tapbp.1 Protein, tapbp Protein, TAPBP Protein, Tapbp Protein

Sujet: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Poids moléculaire: 45.6 kDa

NCBI Accession: NP_003181