TAPBP Protein (His tag)

N° du produit ABIN7317188

Détail du produit

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TAPBP protéine est marqué à la His tag.

Fonction: Recombinant Human TAPBP/ Tapasin Protein (His Tag)

Séquence: Met 1-Val414

Attributs du produit: A DNA sequence encoding the human TAPBP (AAH80574.1) (Met1-Val414) was expressed with a polyhistidine tag at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: TAPBP/ Tapasin (TAPBP Produits)

Synonymes: SI:dZ179B20.1 Protein, SI:dZ179B20.3 Protein, SI:dZ179B20.7 Protein, mhc1uda Protein, mhc1ufa Protein, tpsn Protein, zgc:109814 Protein, tapbp Protein, TAPBP Protein, D17Wsu91e Protein, TPN Protein, NGS17 Protein, TAPA Protein, TPSN Protein, TAP binding protein (tapasin), tandem duplicate 1 Protein, TAP binding protein Protein, tapbp.1 Protein, tapbp Protein, TAPBP Protein, Tapbp Protein

Sujet:

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. 

Synonym: NGS17,TAPA,TPN,TPSN

Poids moléculaire: 43.5 kDa