TARDBP Protein (DYKDDDDK Tag)

N° du produit ABIN2733232

Détail du produit

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Type de proteíne: Recombinant

Origine: Humain

Source: Insect cells (Sf9)

Purification/Conjugué: Cette TARDBP protéine est marqué à la DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TAR DNA binding protein (TARDBP), full length, with C-terminal DDK tag,expressed in sf9 cells (full length, C-term DDK tag) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Abstract: TARDBP Produits

Synonymes: TARDBP Protein, TDP43 Protein, DKFZp459I2127 Protein, tardbp Protein, ALS10 Protein, TDP-43 Protein, 1190002A23Rik Protein, C85084 Protein, Tdp43 Protein, wu:fb77f02 Protein, wu:fc52g10 Protein, TAR DNA binding protein Protein, Tardbp protein Protein, TAR DNA binding protein L homeolog Protein, TAR DNA-binding protein 43-like Protein, TARDBP Protein, tardbp Protein, tardbp.L Protein, Tardbp Protein, LOC100621383 Protein

Sujet: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Poids moléculaire: 45 kDa

NCBI Accession: NP_007366

Pathways: Positive Regulation of Peptide Hormone Secretion