TICAM2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2733703

Détail du produit

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TICAM2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TICAM2 / TRAM protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Autre désignation: Ticam2,tram (TICAM2 Produits)

Synonymes: MyD88-4 Protein, TICAM-2 Protein, TIRAP3 Protein, TIRP Protein, TRAM Protein, B430113A10 Protein, Tirp Protein, Trif Protein, toll like receptor adaptor molecule 2 Protein, toll-like receptor adaptor molecule 2 Protein, TICAM2 Protein, Ticam2 Protein

Sujet: Isoform 2: Proposed to inhibit LPS-TLR4 signaling at the late endosome by interaction with isoform 1 thereby disrupting the association of isoform 1 with TICAM1. May be involved in TLR4 degradation in late endosomes. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 26.7 kDa

NCBI Accession: NP_067681

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades