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TIGAR Protein (Myc-DYKDDDDK Tag)

TIGAR Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2733721
  • Antigène Voir toutes TIGAR Protéines
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    Type de proteíne
    Recombinant
    Origine
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette TIGAR protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human TIGAR protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TIGAR Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    Autre désignation
    Tigar (TIGAR Produits)
    Synonymes
    AA793651 Protein, AI595337 Protein, C79710 Protein, C85509 Protein, Tigar Protein, Trp53 induced glycolysis repulatory phosphatase Protein, Tigar Protein
    Sujet
    This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
    Poids moléculaire
    29.9 kDa
    NCBI Accession
    NP_065108
    Pathways
    L'effet Warburg
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