STING/TMEM173 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2733879

Détail du produit

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette STING/TMEM173 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TMEM173 / STING protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: Tmem173,sting (TMEM173 Produits)

Synonymes: ERIS Protein, MITA Protein, MPYS Protein, NET23 Protein, STING Protein, 2610307O08Rik Protein, Mita Protein, RGD1562552 Protein, transmembrane protein 173 Protein, TMEM173 Protein, Tmem173 Protein

Sujet: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 42 kDa

NCBI Accession: NP_938023

Pathways: Activation of Innate immune Response