STING/TMEM173 Protein (Fc Tag)

N° du produit ABIN7092708

Détail du produit

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette STING/TMEM173 protéine est marqué à la Fc Tag.

Fonction: Recombinant human TMEM173 protein with N-terminal Human Fc tag

Specificité: HFc (Glu99-Ala330) TMEM173 (Leu139-Ser379)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: TMEM173 (TMEM173 Produits)

Synonymes: ERIS Protein, MITA Protein, MPYS Protein, NET23 Protein, STING Protein, 2610307O08Rik Protein, Mita Protein, RGD1562552 Protein, transmembrane protein 173 Protein, TMEM173 Protein, Tmem173 Protein

Sujet: Synonymes: ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173
Description: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Poids moléculaire: predicted molecular mass of 53.2 kDa after removal of the signal peptide.

ID gène: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response