TP53I3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2734083

Détail du produit

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TP53I3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TP53I3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Autre désignation: Tp53i3 (TP53I3 Produits)

Synonymes: MGC82892 Protein, MGC146409 Protein, PIG3 Protein, tumor protein p53 inducible protein 3 Protein, tumor protein p53 inducible protein 3 S homeolog Protein, Tp53I3 Protein, quinone oxidoreductase PIG3 Protein, TP53I3 Protein, tp53i3.S Protein, tp53i3 Protein, tp53I3 Protein

Sujet: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 35.4 kDa

NCBI Accession: NP_004872

Pathways: Signalisation p53