TMX3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2734663

Détail du produit

Antigène: TMX3 (Thioredoxin-Related Transmembrane Protein 3 (TMX3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TMX3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TXNDC10 / TMX3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TMX3 (Thioredoxin-Related Transmembrane Protein 3 (TMX3))

Autre désignation: Txndc10,tmx3 (TMX3 Produits)

Synonymes: tmx3 Protein, pdia13 Protein, txndc10 Protein, txndc10a Protein, TXNDC10 Protein, zgc:110025 Protein, txndc10b Protein, DKFZp469P2316 Protein, PDIA13 Protein, 6430411B10Rik Protein, A730024F05Rik Protein, AV259382 Protein, Txndc10 Protein, mKIAA1830 Protein, thioredoxin-related transmembrane protein 3 S homeolog Protein, thioredoxin related transmembrane protein 3 Protein, thioredoxin related transmembrane protein 3a Protein, thioredoxin-related transmembrane protein 3 L homeolog Protein, thioredoxin-related transmembrane protein 3 Protein, tmx3.S Protein, TMX3 Protein, tmx3a Protein, tmx3.L Protein, tmx3 Protein, Tmx3 Protein

Sujet: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 51.7 kDa

NCBI Accession: NP_061895

Pathways: Cell RedoxHomeostasis