TXNIP Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2734683

Détail du produit

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TXNIP protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TXNIP / VDUP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Autre désignation: Txnip,vdup1 (TXNIP Produits)

Synonymes: EST01027 Protein, HHCPA78 Protein, THIF Protein, VDUP1 Protein, Gm348 Protein, Trf3 Protein, TBP2 Protein, TRF3 Protein, 1200008J08Rik Protein, AA682105 Protein, Hyplip1 Protein, Tbp-2 Protein, Vdup1 Protein, sb:cb368 Protein, txnip Protein, thioredoxin interacting protein Protein, TATA box binding protein like 2 Protein, TATA-box binding protein like 2 Protein, thioredoxin interacting protein L homeolog Protein, thioredoxin interacting protein a Protein, TXNIP Protein, Tbpl2 Protein, TBPL2 Protein, Txnip Protein, txnip.L Protein, txnip Protein, txnipa Protein

Sujet: This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 43.5 kDa

NCBI Accession: NP_006463

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome