XRCC6BP1 Protein (His tag)

N° du produit ABIN2735703

Détail du produit

Antigène: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette XRCC6BP1 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human XRCC6BP1 / KUBP (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Autre désignation: Xrcc6bp1,kubp (XRCC6BP1 Produits)

Synonymes: XRCC6BP1 Protein, MGC108292 Protein, KUB3 Protein, 1110068E08Rik Protein, 2410012H02Rik Protein, kub3 Protein, MGC69108 Protein, ATP23 metallopeptidase and ATP synthase assembly factor homolog Protein, XRCC6 binding protein 1 Protein, ATP23 metallopeptidase and ATP synthase assembly factor homolog L homeolog Protein, Atp23 Protein, ATP23 Protein, atp23 Protein, Xrcc6bp1 Protein, atp23.L Protein

Sujet: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 28.1 kDa

NCBI Accession: NP_150592