IL29 Protéine
IL29
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>97 % as determined by SDS-PAGE and HPLC.
Func
Active
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- Antigène Voir toutes IL29 Protéines
- IL29 (Interleukin 29 (IL29))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func)
- Séquence
- GPVPTSKPTT TGKGCHIGRF KSLSPQELAS FKKARDALEE SLKLKNWSCS SPVFPGNWDL RLLQVRERPV ALEAELALTL KVLEAAAGPA LEDVLDQPLH TLHHILSQLQ ACIQPQPTAG PRPRGRLHHW LHRLQEAPKK ESAGCLEASV TFNLFRLLTR DLKYVADGNL CLRTSTHPES T
- Attributs du produit
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 5 ng/mL, corresponding to a specific activity of ＞ 2.0 x 105 IU/mg.
- Pureté
- >97 % as determined by SDS-PAGE and HPLC.
- Stérilité
- 0.2 μm filtered
- Top Product
- Discover our top product IL29 Protéine
-
Interleukin 29 (IL29) (AA 22-200) protein (His tag)
IL29 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- IL29 (Interleukin 29 (IL29))
- Autre désignation
- IFNL1 (IL29 Produits)
- Synonymes
- IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
- Sujet
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Relevance: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Synonyms: IFN-lambda-1, Interleukin-29, IL-29 - Poids moléculaire
- 19.8 kDa
- UniProt
- Q8IU54
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