DR3/LARD Protein (AA 20-203) (Fc Tag)

N° du produit ABIN2870800

Détail du produit

Antigène: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Type de proteíne: Recombinant

Attributs du protein: AA 20-203

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette DR3/LARD protéine est marqué à la Fc Tag.

Séquence: AA 20-203

Attributs du produit: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.3 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE).

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Détail du antigène

Antigène: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Autre désignation: DR3 / TNFRSF25 (TNFRSF25 Produits)

Synonymes: APO-3 Protein, DDR3 Protein, DR3 Protein, LARD Protein, TNFRSF12 Protein, TR3 Protein, TRAMP Protein, WSL-1 Protein, WSL-LR Protein, Tnfrsf12 Protein, Wsl Protein, TNFRSF25 Protein, TNF receptor superfamily member 25 Protein, tumor necrosis factor receptor superfamily, member 25 Protein, TNFRSF25 Protein, Tnfrsf25 Protein

Sujet: Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.

Poids moléculaire: 46.3 kDa

UniProt: G7NTB5

Pathways: Apoptose