FAH Protein (AA 2-419) (His tag)

N° du produit ABIN1691329

Détail du produit

Antigène: FAH (Fumarylacetoacetate Hydrolase (Fumarylacetoacetase) (FAH))

Type de proteíne: Recombinant

Attributs du protein: AA 2-419

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette FAH protéine est marqué à la His tag.

Fonction: Recombinant Human Fumarylacetoacetase/FAH (C-6His)

Séquence: SFIPVAEDSD FPIHNLPYGV FSTRGDPRPR IGVAIGDQIL DLSIIKHLFT GPVLSKHQDV FNQPTLNSFM GLGQAAWKEA RVFLQNLLSV SQARLRDDTE LRKCAFISQA SATMHLPATI GDYTDFYSSR QHATNVGIMF RDKENALMPN WLHLPVGYHG RASSVVVSGT PIRRPMGQMK PDDSKPPVYG ACKLLDMELE MAFFVGPGNR LGEPIPISKA HEHIFGMVLM NDWSARDIQK WEYVPLGPFL GKSFGTTVSP WVVPMDALMP FAVPNPKQDP RPLPYLCHDE PYTFDINLSV NLKGEGMSQA ATICKSNFKY MYWTMLQQLT HHSVNGCNLR PGDLLASGTI SGPEPENFGS MLELSWKGTK PIDLGNGQTR KFLLDGDEVI ITGYCQGDGY RIGFGQCAGK VLPALLPSVD HHHHHH

Attributs du produit: Recombinant Human Fumarylacetoacetase/FAH is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser2-Ser419) of Human FAH fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: FAH (Fumarylacetoacetate Hydrolase (Fumarylacetoacetase) (FAH))

Autre désignation: Fumarylacetoacetase (FAH Produits)

Synonymes: CG14993 Protein, Dmel\\CG14993 Protein, dfaa Protein, l(3)64Al Protein, l(3)SH11 Protein, PSPTO3550 Protein, fb59b12 Protein, wu:fb59b12 Protein, zgc:55316 Protein, FAA Protein, Fumarylacetoacetase Protein, FumarylAcetoacetate Hydrolase Protein, fumarylacetoacetase Protein, fumarylacetoacetate hydrolase Protein, fumarylacetoacetate hydrolase (fumarylacetoacetase) Protein, fumarylacetoacetate hydrolase (fumarylacetoacetase) L homeolog Protein, Faa Protein, fah-1 Protein, fahA Protein, hmgB Protein, Ndas_1870 Protein, Lbys_3503 Protein, Riean_0663 Protein, Ftrac_0820 Protein, Celal_3675 Protein, Celly_2655 Protein, Weevi_0208 Protein, Fluta_2435 Protein, Halhy_2019 Protein, Lacal_2931 Protein, FsymDg_1892 Protein, Fah Protein, fah Protein, fah.L Protein, FAH Protein

Sub Type: Fusionprotein

Sujet: Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. Defects in Fumarylacetoacetase cause tyrosinemia type 1, which is congenital metabolism defect characterized by elevated levels of tyrosine in the blood and urine, and hepatorenal manifestations. Typical features include renal tubular injury, self-mutilation, hepatic necrosis, episodic weakness, and seizures.
Alternative Names: Fumarylacetoacetase, FAA, Beta-Diketonase, Fumarylacetoacetate Hydrolase, FAH

Poids moléculaire: 47.4 kDa

UniProt: P16930