BTN1A1 Protein (AA 27-242) (Fc Tag)

N° du produit ABIN4949082

Détail du produit

Antigène: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Type de proteíne: Recombinant

Attributs du protein: AA 27-242

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette BTN1A1 protéine est marqué à la Fc Tag.

Application: Functional Studies (Func)

Séquence: AA 27-242

Attributs du produit: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE).

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Détail du antigène

Antigène: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Autre désignation: BTN1A1 (BTN1A1 Produits)

Synonymes: BT Protein, BTN Protein, Btn Protein, BTN1A1 Protein, TVC Protein, butyrophilin subfamily 1 member A1 Protein, butyrophilin, subfamily 1, member A1 Protein, zgc:162154 Protein, BTN1A1 Protein, Btn1a1 Protein, btn1a1 Protein, zgc:162154 Protein

Sujet: Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Poids moléculaire: 50.6 kDa

Pathways: Activated T Cell Proliferation