Poliovirus Receptor Protein (PVR) (AA 21-343) (Fc Tag)
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- Antigène Voir toutes Poliovirus Receptor (PVR) Protéines
- Poliovirus Receptor (PVR)
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 21-343
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Poliovirus Receptor protéine est marqué à la Fc Tag.
- Application
- Functional Studies (Func)
- Séquence
- AA 21-343
- Attributs du produit
- This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 62.2 kDa. As a result of glycosylation, The protein migrates as 70-100 kDa under reducing (R) condition and 130-160 kDa under non-reducing (NR) condition on SDS-PAGE gel.
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product PVR Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- Poliovirus Receptor (PVR)
- Autre désignation
- CD155 (PVR Produits)
- Synonymes
- PVR Protein, CD155 Protein, HVED Protein, NECL5 Protein, Necl-5 Protein, PVS Protein, TAGE4 Protein, 3830421F03Rik Protein, D7Ertd458e Protein, Taa1 Protein, Tage4 Protein, mE4 Protein, necl-5 Protein, poliovirus receptor Protein, PVR Protein, Pvr Protein
- Sujet
- CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
- Poids moléculaire
- 62.2 kDa
- NCBI Accession
- NP_006496
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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