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AGRP Protein (AA 21-132) (His-SUMO Tag)

AGRP Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709009
  • Antigène Voir toutes AGRP Protéines
    AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 21-132
    Origine
    • 8
    • 4
    • 2
    • 1
    • 1
    Humain
    Source
    • 6
    • 5
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette AGRP protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    AQMGLAPMEG IRRPDQALLP ELPGLGLRAP LKKTTAEQAE EDLLQEAQAL AEVLDLQDRE PRSSRRCVRL HESCLGQQVP CCDPCATCYC RFFNAFCYCR KLGTAMNPCS RT
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product AGRP Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
    Autre désignation
    AGRP (AGRP Produits)
    Synonymes
    AGRT Protein, ART Protein, ASIP2 Protein, Agrt Protein, Art Protein, agouti related neuropeptide Protein, agouti-related protein pseudogene Protein, AGRP Protein, Agrp Protein, LOC100352591 Protein
    Sujet
    Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin syst. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R . Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
    Poids moléculaire
    28.5 kDa
    UniProt
    O00253
    Pathways
    Feeding Behaviour, Photoperiodism
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