AGRP Protein (AA 21-132) (His-SUMO Tag)
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- Antigène Voir toutes AGRP Protéines
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 21-132
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette AGRP protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- AQMGLAPMEG IRRPDQALLP ELPGLGLRAP LKKTTAEQAE EDLLQEAQAL AEVLDLQDRE PRSSRRCVRL HESCLGQQVP CCDPCATCYC RFFNAFCYCR KLGTAMNPCS RT
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product AGRP Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Autre désignation
- AGRP (AGRP Produits)
- Synonymes
- AGRT Protein, ART Protein, ASIP2 Protein, Agrt Protein, Art Protein, agouti related neuropeptide Protein, agouti-related protein pseudogene Protein, AGRP Protein, Agrp Protein, LOC100352591 Protein
- Sujet
- Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin syst. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R . Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
- Poids moléculaire
- 28.5 kDa
- UniProt
- O00253
- Pathways
- Feeding Behaviour, Photoperiodism
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