AOX1 Protein (AA 236-421, PCMH-type domain) (His tag)

N° du produit ABIN5709049

Détail du produit

Antigène: AOX1 (Aldehyde Oxidase 1 (AOX1))

Type de proteíne: Recombinant

Attributs du protein: PCMH-type domain, AA 236-421

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette AOX1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: FGSERMMWFS PVTLKELLEF KFKYPQAPVI MGNTSVGPEV KFKGVFHPVI ISPDRIEELS VVNHAYNGLT LGAGLSLAQV KDILADVVQK LPEEKTQMYH ALLKHLGTLA GSQIRNMASL GGHIISRHPD SDLNPILAVG NCTLNLLSKE GKRQIPLNEQ FLSKCPNADL KPQEILVSVN IPYSRK

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: AOX1 (Aldehyde Oxidase 1 (AOX1))

Autre désignation: AOXA (AOX1 Produits)

Synonymes: AO Protein, AOH1 Protein, AI196512 Protein, AI255253 Protein, Ao Protein, Aox-1 Protein, Aox-2 Protein, Aox2 Protein, Moro Protein, Ro Protein, aoh1 Protein, AAO1 Protein, ALDEHYDE OXIDASE Protein, AOalpha Protein, ARABIDOPSIS THALIANA ALDEHYDE OXIDASE 1 Protein, AT-AO1 Protein, ATAO Protein, Arabidopsis thaliana aldehyde oxidase 1 Protein, AtAO1 Protein, F22D1.130 Protein, F22D1_130 Protein, aldehyde oxidase 1 Protein, aldehyde oxidase alpha Protein, AOX Protein, Aldox Protein, Ao-1 Protein, Aox Protein, aldox Protein, aldehyde oxidase 1 Protein, aldehyde oxidase 1 L homeolog Protein, Aldehyde oxidase at 89A Protein, hypothetical protein Protein, alternative oxidase Protein, AOX1 Protein, Aox1 Protein, aox1.L Protein, AO1 Protein, Aldox89A Protein, POPTR_0009s15560g Protein

Sujet: Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis

Poids moléculaire: 24.7 kDa

UniProt: Q06278