EIF4EBP3 Protein (AA 1-100, full length) (His-SUMO Tag)

N° du produit ABIN5709457

Détail du produit

Antigène: EIF4EBP3 (Eukaryotic Translation Initiation Factor 4E Binding Protein 3 (EIF4EBP3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-100, full length

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette EIF4EBP3 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: MSTSTSCPIP GGRDQLPDCY STTPGGTLYA TTPGGTRIIY DRKFLLECKN SPIARTPPCC LPQIPGVTTP PTAPLSKLEE LKEQETEEEI PDDAQFEMDI

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: EIF4EBP3 (Eukaryotic Translation Initiation Factor 4E Binding Protein 3 (EIF4EBP3))

Autre désignation: 4EBP3 (EIF4EBP3 Produits)

Synonymes: zgc:103720 Protein, 4E-BP3 Protein, 4EBP3 Protein, 4e-bp3 Protein, eukaryotic translation initiation factor 4E binding protein 3 Protein, eif4ebp3 Protein, Eif4ebp3 Protein, EIF4EBP3 Protein

Sujet: Repressor of translation initiation that regulates EIF4E activity by preventing its assbly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.

Poids moléculaire: 26.87 kDa

UniProt: O60516