GDF9 Protein (AA 320-454) (GST tag)

N° du produit ABIN5709565

Détail du produit

Antigène: GDF9 (Growth Differentiation Factor 9 (GDF9))

Type de proteíne: Recombinant

Attributs du protein: AA 320-454

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GDF9 protéine est marqué à la GST tag.

Application: SDS-PAGE (SDS)

Séquence: GQETVSSELK KPLGPASFNL SEYFRQFLLP QNECELHDFR LSFSQLKWDN WIVAPHRYNP RYCKGDCPRA VGHRYGSPVH TMVQNIIYEK LDSSVPRPSC VPAKYSPLSV LTIEPDGSIA YKEYEDMIAT KCTCR

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: GDF9 (Growth Differentiation Factor 9 (GDF9))

Autre désignation: GDF9 (GDF9 Produits)

Synonymes: GDF-9 Protein, zgc:123030 Protein, Gdf-9 Protein, growth differentiation factor 9 Protein, GDF9 Protein, gdf9 Protein, Gdf9 Protein

Sujet: Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

Poids moléculaire: 42.9 kDa

UniProt: O60383