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HAS2 Protein (AA 67-374, Cytoplasmic Domain, Cytosolic) (His tag)

HAS2 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709643
  • Antigène Voir toutes HAS2 Protéines
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    Type de proteíne
    Recombinant
    Attributs du protein
    Cytosolic, AA 67-374, Cytoplasmic Domain
    Origine
    • 4
    • 3
    Souris
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette HAS2 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    EHRKMKKSLE TPIKLNKTVA LCIAAYQEDP DYLRKCLQSV KRLTYPGIKV VMVIDGNSDD DLYMMDIFSE VMGRDKSATY IWKNNFHEKG PGETEESHKE SSQHVTQLVL SNKSICIMQK WGGKREVMYT AFRALGRSVD YVQVCDSDTM LDPASSVEMV KVLEEDPMVG GVGGDVQILN KYDSWISFLS SVRYWMAFNI ERACQSYFGC VQCISGPLGM YRNSLLHEFV EDWYNQEFMG NQCSFGDDRH LTNRVLSLGY ATKYTARSKC LTETPIEYLR WLNQQTRWSK SYFREWLYNA MWFHKHHL
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product HAS2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    Autre désignation
    HYAS2 (HAS2 Produits)
    Synonymes
    DG42 Protein, XHas2 Protein, Has2 Protein, hyaluronan synthase 2 Protein, hyaluronan synthase 2 S homeolog Protein, has2 Protein, HAS2 Protein, Has2 Protein, SHAS2 Protein, has2.S Protein
    Sujet
    Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix.
    Poids moléculaire
    40 kDa
    UniProt
    P70312
    Pathways
    Glycosaminoglycan Metabolic Process
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