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KIAA0101 Protein (AA 1-111, full length) (GST tag)

PAF Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709801
  • Antigène Voir toutes KIAA0101 (PAF) Protéines
    KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-111, full length
    Origine
    • 5
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette KIAA0101 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MVRTKADSVP GTYRKVVAAR APRKVLGSST SATNSTSVSS RKAENKYAGG NPVCVRPTPK WQKGIGEFFR LSPKDSEKEN QIPEEAGSSG LGKAKRKACP LQPDHTNDEK E
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product PAF Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))
    Autre désignation
    PAF15 (PAF Produits)
    Synonymes
    NS5ATP9 Protein, OEATC Protein, OEATC-1 Protein, OEATC1 Protein, PAF Protein, PAF15 Protein, p15(PAF) Protein, p15/PAF Protein, p15PAF Protein, paf Protein, Paf Protein, AA409629 Protein, Ns5apt9 Protein, Ns5atp9 Protein, mKIAA0101 Protein, Kiaa0101 Protein, PCNA clamp associated factor Protein, PCNA clamp associated factor S homeolog Protein, PCLAF Protein, pclaf Protein, pclaf.S Protein, Pclaf Protein
    Sujet
    PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
    Poids moléculaire
    39.4 kDa
    UniProt
    Q15004
    Pathways
    Chromatin Binding
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