REG3g Protein (AA 27-174) (His tag)

N° du produit ABIN5710242

Détail du produit

Antigène: REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))

Type de proteíne: Recombinant

Attributs du protein: AA 27-174

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette REG3g protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: EDAKEDVPTS RISCPKGSRA YGSYCYALFS VSKSWFDADL ACQKRPSGHL VSVLSGSEAS FVSSLIKSSG NSGQNVWIGL HDPTLGQEPN RGGWEWSNAD VMNYFNWETN PSSVSGSHCG TLTRASGFLR WRENNCISEL PYVCKFKA

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))

Autre désignation: REG3G (REG3g Produits)

Synonymes: LPPM429 Protein, PAP IB Protein, PAP-1B Protein, PAP1B Protein, PAPIB Protein, REG III Protein, REG-III Protein, UNQ429 Protein, AI449515 Protein, PAPIII Protein, Pap3 Protein, REG3A Protein, regenerating family member 3 gamma Protein, regenerating islet-derived 3 gamma Protein, REG3G Protein, Reg3g Protein

Sujet: Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury .

Poids moléculaire: 20.34 kDa

UniProt: P42854

Pathways: Activation of Innate immune Response