RBBP7 Protein (AA 1-425, full length) (His-SUMO Tag)

N° du produit ABIN5711301

Détail du produit

Antigène: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Type de proteíne: Recombinant

Attributs du protein: full length, AA 1-425

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RBBP7 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: MASKEMFEDT VEERVINEEY KIWKKNTPFL YDLVMTHALQ WPSLTVQWLP EVTKPEGKDY ALHWLVLGTH TSDEQNHLVV ARVHIPNDDA QFDASHCDSD KGEFGGFGSV TGKIECEIKI NHEGEVNRAR YMPQNPHIIA TKTPSSDVLV FDYTKHPAKP DPSGECNPDL RLRGHQKEGY GLSWNSNLSG HLLSASDDHT VCLWDINAGP KEGKIVDAKA IFTGHSAVVE DVAWHLLHES LFGSVADDQK LMIWDTRSNT TSKPSHLVDA HTAEVNCLSF NPYSEFILAT GSADKTVALW DLRNLKLKLH TFESHKDEIF QVHWSPHNET ILASSGTDRR LNVWDLSKIG EEQSAEDAED GPPELLFIHG GHTAKISDFS WNPNEPWVIC SVSEDNIMQI WQMAENIYND EESDVTTSEL EGQGS

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Autre désignation: RBBP7 (RBBP7 Produits)

Synonymes: RbAp46 Protein, AA409861 Protein, AI173248 Protein, AU019541 Protein, BB114024 Protein, mRbAp46 Protein, rbap46 Protein, RBBP7 Protein, RBBP-7 Protein, Caf1 Protein, rbbp7 Protein, wu:fa13g08 Protein, wu:fb50h10 Protein, wu:fc29d09 Protein, zgc:56477 Protein, zgc:85617 Protein, CaO19.2146 Protein, RB binding protein 7, chromatin remodeling factor Protein, retinoblastoma binding protein 7, chromatin remodeling factor Protein, retinoblastoma binding protein 7 L homeolog Protein, retinoblastoma binding protein 7 Protein, retinoblastoma binding protein 4, like Protein, histone-binding protein RBBP7 Protein, Hat2p Protein, RBBP7 Protein, Rbbp7 Protein, rbbp7.L Protein, rbbp7 Protein, rbb4l Protein, LOC108708306 Protein, HAT2 Protein

Sujet: Core histone-binding subunit that may target chromatin rodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assbly following DNA replication, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome rodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome rodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome rodeling factor) complex.

Poids moléculaire: 63.8 kDa

UniProt: Q16576