GCKR Protein (AA 1-625, full length) (His-SUMO Tag)
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- Antigène Voir toutes GCKR Protéines
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-625, full length
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette GCKR protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MPGTKRFQHV IETPEPGKWE LSGYEAAVPI TEKSNPLTQD LDKADAENIV RLLGQCDAEI FQEEGQALST YQRLYSESIL TTMVQVAGKV QEVLKEPDGG LVVLSGGGTS GRMAFLMSVS FNQLMKGLGQ KPLYTYLIAG GDRSVVASRE GTEDSALHGI EELKKVAAGK KRVIVIGISV GLSAPFVAGQ MDCCMNNTAV FLPVLVGFNP VSMARNDPIE DWSSTFRQVA ERMQKMQEKQ KAFVLNPAIG PEGLSGSSRM KGGSATKILL ETLLLAAHKT VDQGIAASQR CLLEILRTFE RAHQVTYSQS PKIATLMKSV STSLEKKGHV YLVGWQTLGI IAIMDGVECI HTFGADFRDV RGFLIGDHSD MFNQKAELTN QGPQFTFSQE DFLTSILPSL TEIDTVVFIF TLDDNLTEVQ TIVEQVKEKT NHIQALAHST VGQTLPIPLK KLFPSIISIT WPLLFFEYEG NFIQKFQREL STKWVLNTVS TGAHVLLGKI LQNHMLDLRI SNSKLFWRAL AMLQRFSGQS KARCIESLLR AIHFPQPLSD DIRAAPISCH VQVAHEKEQV IPIALLSLLF RCSITEAQAH LAAAPSVCEA VRSALAGPGQ KRTADPLEIL EPDVQ
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product GCKR Protéine
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Glucokinase (Hexokinase 4) Regulator (GCKR) (AA 1-625) protein (Strep Tag)
Crystallography grade GCKR Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Glucokinase (Hexokinase 4) Regulator (GCKR) (AA 1-587) protein (His tag)Crystallography grade GCKR Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glucokinase (Hexokinase 4) Regulator (GCKR) (AA 1-625), (full length) protein (His tag)GCKR Origine: Humain Hôte: Levure Recombinant > 90 % SDS
Glucokinase (Hexokinase 4) Regulator (GCKR) protein (Myc-DYKDDDDK Tag)GCKR Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Autre désignation
- GCKR (GCKR Produits)
- Synonymes
- FGQTL5 Protein, GKRP Protein, GLRE Protein, gckr Protein, glucokinase regulator Protein, glucokinase regulatory protein Protein, glucokinase regulator L homeolog Protein, GCKR Protein, Gckr Protein, gckr.L Protein
- Sujet
- Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
- Poids moléculaire
- 84.6 kDa
- UniProt
- Q14397
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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