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NMNAT3 Protein (AA 1-215, Isoform 2) (His-SUMO Tag)

NMNAT3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711591
  • Antigène Voir toutes NMNAT3 Protéines
    NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-215, Isoform 2
    Origine
    • 4
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette NMNAT3 protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MYQVIQGIIS PVNDTYGKKD LAASHHRVAM ARLALQTSDW IRVDPWESEQ AQWMETVKVL RHHHSKLLRS PPQMEGPDHG KALFSTPAAV PELKLLCGAD VLKTFQTPNL WKDAHIQEIV EKFGLVCVGR VGHDPKGYIA ESPILRMHQH NIHLAKEPVQ NEISATYIRR ALGQGQSVKY LIPDAVITYI KDHGLYTKGS TWKGKSTQST EGKTS
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product NMNAT3 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
    Autre désignation
    NMNA3 (NMNAT3 Produits)
    Synonymes
    PNAT-3 Protein, PNAT3 Protein, 4933408N02Rik Protein, nicotinamide nucleotide adenylyltransferase 3 Protein, si:ch73-170l17.1 Protein, Nmnat3 Protein, NMNAT3 Protein, si:ch73-170l17.1 Protein
    Sujet
    Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, can use NAD+, NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NaADP+. Protects against axonal degeneration following injury.
    Poids moléculaire
    40.1 kDa
    UniProt
    Q96T66
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