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ALKBH3 Protein (AA 1-170) (His-SUMO Tag)

ALKBH3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711658
  • Antigène Voir toutes ALKBH3 Protéines
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-170
    Origine
    • 4
    • 1
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette ALKBH3 protéine est marqué à la His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MEEKRRRARV QGAWAAPVKS QAIAQPATTA KSHLHQKPGQ TWKNKEHHLS DREFVFKEPQ QVVRRAPEPR VIEEGVYEIS LSPTGVSRVC LYPGFVDVKE ADWILEQLCQ DVPWKQRTGI REDSILQLTF KKSAPVSGTA TAPQSCWYER PSPPHIPGPA ILTRTRLWAP
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product ALKBH3 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    Autre désignation
    ALKB3 (ALKBH3 Produits)
    Synonymes
    ABH3 Protein, DEPC-1 Protein, DEPC1 Protein, PCA1 Protein, 1700108H04Rik Protein, 1810020C19Rik Protein, Abh3 Protein, mABH3 Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase L homeolog Protein, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase Protein, alkbh3.L Protein, ALKBH3 Protein, Alkbh3 Protein
    Sujet
    Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative dethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
    Poids moléculaire
    35.3 kDa
    UniProt
    Q96Q83
    Pathways
    Réparation de l'ADN
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