Histone H2B Type 1-C/E/F/G/I (LOC100407767) (AA 2-125) protein (GST tag)

N° du produit ABIN5712177

Détail du produit

Antigène: Histone H2B Type 1-C/E/F/G/I (LOC100407767)

Type de proteíne: Recombinant

Attributs du protein: AA 2-125

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: GST tag

Application: SDS-PAGE (SDS)

Séquence: PEPAKSAPAP KKGSKKAVTK AQKKDGKKRK RSRKESYSVY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSS

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: Histone H2B Type 1-C/E/F/G/I (LOC100407767)

Autre désignation: H2B1C (LOC100407767 Produits)

Synonymes: H2B.1 Protein, H2B/l Protein, H2BFL Protein, dJ221C16.3 Protein, histone cluster 1 H2B family member c Protein, HIST1H2BC Protein

Sujet: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Poids moléculaire: 41 kDa

UniProt: P62807