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COBRA1 Protein (AA 8-199, partial) (GST tag)

COBRA1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN4976373
  • Antigène Voir toutes COBRA1 Protéines
    COBRA1 (Cofactor of BRCA1 (COBRA1))
    Type de proteíne
    Recombinant
    Attributs du protein
    partial, AA 8-199
    Origine
    • 4
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette COBRA1 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    LGVANGEDLK ETLTNCTEPL KAIEQFQTEN GVLLPSLQSA LPFLDLHGTP RLEFHQSVFD ELRDKLLERV SAIASEGKAE ERYKKLEDLL EKSFSLVKMP SLQPVVMCVM KHLPKVPEKK LKLVMADKEL YRACAVEVKR QIWQDNQALF GDEVSPLLKQ YILEKESALF STELSVLHNF FSPSPKTRRQ GE
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product COBRA1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    COBRA1 (Cofactor of BRCA1 (COBRA1))
    Autre désignation
    NELFB (COBRA1 Produits)
    Synonymes
    LOC100219583 Protein, COBRA1 Protein, NELF-B Protein, bZ1O1.4 Protein, cobra1 Protein, cobra2 Protein, fe01e12 Protein, wu:fe01e12 Protein, zgc:55628 Protein, MGC131073 Protein, Cobra1 Protein, RGD1307832 Protein, A730008L03Rik Protein, AB041607 Protein, AI663983 Protein, Nelf-b Protein, cofactor of BRCA1 Protein, negative elongation factor complex member B Protein, negative elongation factor complex member B L homeolog Protein, LOC100219583 Protein, NELFB Protein, nelfb Protein, nelfb.L Protein, Nelfb Protein
    Sujet
    Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.
    Poids moléculaire
    49.2 kDa
    UniProt
    Q8WX92
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