COBRA1 Protein (AA 8-199, partial) (GST tag)
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- Antigène Voir toutes COBRA1 Protéines
- COBRA1 (Cofactor of BRCA1 (COBRA1))
- Type de proteíne
- Recombinant
- Attributs du protein
- partial, AA 8-199
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette COBRA1 protéine est marqué à la GST tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- LGVANGEDLK ETLTNCTEPL KAIEQFQTEN GVLLPSLQSA LPFLDLHGTP RLEFHQSVFD ELRDKLLERV SAIASEGKAE ERYKKLEDLL EKSFSLVKMP SLQPVVMCVM KHLPKVPEKK LKLVMADKEL YRACAVEVKR QIWQDNQALF GDEVSPLLKQ YILEKESALF STELSVLHNF FSPSPKTRRQ GE
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product COBRA1 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- COBRA1 (Cofactor of BRCA1 (COBRA1))
- Autre désignation
- NELFB (COBRA1 Produits)
- Synonymes
- LOC100219583 Protein, COBRA1 Protein, NELF-B Protein, bZ1O1.4 Protein, cobra1 Protein, cobra2 Protein, fe01e12 Protein, wu:fe01e12 Protein, zgc:55628 Protein, MGC131073 Protein, Cobra1 Protein, RGD1307832 Protein, A730008L03Rik Protein, AB041607 Protein, AI663983 Protein, Nelf-b Protein, cofactor of BRCA1 Protein, negative elongation factor complex member B Protein, negative elongation factor complex member B L homeolog Protein, LOC100219583 Protein, NELFB Protein, nelfb Protein, nelfb.L Protein, Nelfb Protein
- Sujet
- Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.
- Poids moléculaire
- 49.2 kDa
- UniProt
- Q8WX92
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