TMED9
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Stock
-80 °C,4 °C,-20 °C
Stockage commentaire
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Antigène
TMED9
(Transmembrane Emp24 Protein Transport Domain Containing 9 (TMED9))
GMP25 Protein, HSGP25L2G Protein, p25 Protein, 2400003B06Rik Protein, RGD1307627 Protein, sb:cb294 Protein, wu:fi23g02 Protein, zgc:110394 Protein, zgc:110656 Protein, Xp24a2 Protein, Xp24alpha2 Protein, tmed9 Protein, transmembrane p24 trafficking protein 9 Protein, transmembrane emp24 protein transport domain containing 9 Protein, transmembrane p24 trafficking protein 9 S homeolog Protein, TMED9 Protein, Tmed9 Protein, tmed9 Protein, tmed9.S Protein
Sujet
Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to mbranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi mbranes, specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular mbranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.