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BRMS1 Protein (AA 1-235, partial) (GST tag)

BRMS1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5712363
  • Antigène Voir toutes BRMS1 Protéines
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-235, partial
    Origine
    • 4
    • 1
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette BRMS1 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE YTEPLGGLQR SLKIRIQVAG IYKGFCLDVI RNKYECELQG AKQHLESEKL LLYDTLQGEL QERIQRLEED RQSLDLSSEW WDDKLHARGS SRSWDSLPPS KRKKAPLVSG PYIVYMLQEI DILEDWTAIK KARAA
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product BRMS1 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Autre désignation
    BRMS1 (BRMS1 Produits)
    Synonymes
    MGC98869 Protein, BRMS1 Protein, BRMS1L Protein, AV003220 Protein, AW554636 Protein, si:zc188c22.3 Protein, si:zc194c5.2 Protein, wu:fb57b08 Protein, zgc:56414 Protein, breast cancer metastasis suppressor 1 Protein, breast cancer metastasis-suppressor 1 Protein, breast cancer metastasis suppressor 1 L homeolog Protein, BRMS1 Protein, Brms1 Protein, brms1.L Protein, brms1 Protein
    Sujet
    Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
    Poids moléculaire
    54.7 kDa
    UniProt
    Q9HCU9
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