BRMS1 Protein (AA 1-246) (T7 tag)
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- Antigène Voir toutes BRMS1 Protéines
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-246
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette BRMS1 protéine est marqué à la T7 tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MASMTGGQQM GRGSHMPVQP PSKDTEEMEA EGDSAAEMNG EEEESEEERS GSQTESEEES SEMDDEDYER RRSECVSEML DLEKQFSELK EKLFRERLSQ LRLRLEEVGA ERAPEYTEPL GGLQRSLKIR IQVAGIYKGF CLDVIRNKYE CELQGAKQHL ESEKLLLYDT LQGELQERIQ RLEEDRQSLD LSSEWWDDKL HARGSSRSWD SLPPSKRKKA PLVSGPYIVY MLQEIDILED WTAIKKARAA VSPQKRKSDG P
- Pureté
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product BRMS1 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- Autre désignation
- BRMS1 (BRMS1 Produits)
- Synonymes
- MGC98869 Protein, BRMS1 Protein, BRMS1L Protein, AV003220 Protein, AW554636 Protein, si:zc188c22.3 Protein, si:zc194c5.2 Protein, wu:fb57b08 Protein, zgc:56414 Protein, breast cancer metastasis suppressor 1 Protein, breast cancer metastasis-suppressor 1 Protein, breast cancer metastasis suppressor 1 L homeolog Protein, BRMS1 Protein, Brms1 Protein, brms1.L Protein, brms1 Protein
- Sujet
- BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. Recombinant human BRMS1 protein, fused to T7-tag at N-terminus, was expressed in E.coli .
- Poids moléculaire
- 29.9 kDa (261aa)
- NCBI Accession
- NP_056214
- UniProt
- Q9HCU9
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