PSMA Protein (AA 48-750, partial) (His tag)

N° du produit ABIN5712794

Détail du produit

Antigène: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Type de proteíne: Recombinant

Attributs du protein: AA 48-750, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PSMA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: EATNITPKHN MKAFLDELKA ENIKKFLYNF TQIPHLAGTE QNFQLAKQIQ SQWKEFGLDS VELAHYDVLL SYPNKTHPNY ISIINEDGNE IFNTSLFEPP PPGYENVSDI VPPFSAFSPQ GMPEGDLVYV NYARTEDFFK LERDMKINCS GKIVIARYGK VFRGNKVKNA QLAGAKGVIL YSDPADYFAP GVKSYPDGWN LPGGGVQRGN ILNLNGAGDP LTPGYPANEY AYRRGIAEAV GLPSIPVHPI GYYDAQKLLE KMGGSAPPDS SWRGSLKVPY NVGPGFTGNF STQKVKMHIH STNEVTRIYN VIGTLRGAVE PDRYVILGGH RDSWVFGGID PQSGAAVVHE IVRSFGTLKK EGWRPRRTIL FASWDAEEFG LLGSTEWAEE NSRLLQERGV AYINADSSIE GNYTLRVDCT PLMYSLVHNL TKELKSPDEG FEGKSLYESW TKKSPSPEFS GMPRISKLGS GNDFEVFFQR LGIASGRARY TKNWETNKFS GYPLYHSVYE TYELVEKFYD PMFKYHLTVA QVRGGMVFEL ANSIVLPFDC RDYAVVLRKY ADKIYSISMK HPQEMKTYSV SFDSLFSAVK NFTEIASKFS ERLQDFDKSN PIVLRMMNDQ LMFLERAFID PLGLPDRPFY RHVIYAPSSH NKYAGESFPG IYDALFDIES KVDPSKAWGE VKRQIYVAAF TVQAAAETLS EVA

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Autre désignation: FOLH1 (FOLH1 Produits)

Synonymes: FGCP Protein, FOLH Protein, GCP2 Protein, GCPII Protein, NAALAD1 Protein, NAALAdase Protein, PSM Protein, PSMA Protein, mGCP Protein, mopsm Protein, Naalad Protein, putative N-acetylated-alpha-linked acidic dipeptidase Protein, folate hydrolase 1B Protein, folate hydrolase 1 Protein, folate hydrolase (prostate-specific membrane antigen) 1 Protein, LOC451185 Protein, FOLH1B Protein, FOLH1 Protein, Folh1 Protein

Sujet: Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression.Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

Poids moléculaire: 83.2 kDa

UniProt: Q04609